What is Bactrim? How to Treat with Generic Trimethoprim.

Generic Bactrim (Trimethoprim 480 mg) guide:

More facts about Generic Bactrim (Trimethoprim 480 mg):

What is Generic Bactrim? Is it different from the branded drug?

The branded drug Bactrim is a bacteriostatic antibiotic based on the active substance called Trimethoprim. Bactrim is not the original name, it is a brand owned by a certain company while the same drugs under the names such as Trimethoprim, Ipral, Trimopan, and others are used all over the world. First, the medication was used in 1962 in Finland. Currently, it is included in the list of Essential Medicines compiled by the World Health Organization. It means, that the medication is considered a crucial part of health care system of every country.

Generic drugs are analogs of the branded medication manufactured and sold under different names. They do not differ from the branded drug by quality and effect but are usually less advertised and therefore, cheaper. In your country you can find some of the available generics. But not all of them are available in all countries. Some generics are registered only in a certain region or a country and are much cheaper than the internationally sold drugs for obvious reasons such as fewer applications for approval, transportation, promotion, and so on. You can also enjoy their lower prices if you buy Bactrim online from our drugstore.

When should you buy Generic Bactrim and use it?

First of all, we need to warn you that inappropriate or incorrect use of antibiotics is very dangerous for your health. Not only they can harm your health instantly and irreversibly but also they can make the bacteria resistant to certain substances and in a life-threatening situation antibacterial treatment will not be effective. You should never use antibiotics for a common cold or flu as these are viral infections. If the symptoms do not go away for more than 2 weeks, then you need to go to a doctor and make a susceptibility test which will show what antibiotics you should use.

The best time to buy Bactrim is when your doctor appoints you the therapy with the drug. In general, the medication is a first line choice for bladder and urinary tract infections and a second line choice for other conditions such as otitis media (middle ear infections) and diarrhea induced by certain bacteria.

The medication can be also used as a part of combination therapy of pneumonia in patients with HIV and AIDS.

How should you use Bactrim (Trimethoprim)?

The medication can be used both in adults and children over 12 years of age. Here you can find the generally recommended dosages indicated on the medicine’s label.

Adults:
- Uncomplicated urinary tract infection treatment susceptible to the drug: the drug should be taken orally in the dosage of 100 mg 2 times a day with an interval of 12 hours or 200 mg once a day for ten days.

Children over 12 years and younger than 18:
- Uncomplicated urinary tract infection treatment susceptible to the drug: the drug should be taken orally in the dosage of 100 mg 2 times a day with an interval of 12 hours or 200 mg once a day for ten days;
- Treatment of middle ear infection in children older than 6 months of age: the dosage is calculated in the amount of 5 milligrams per kilogram of the body weight administered in a form of suspension prepared from the tablets 2 times a day with an interval of 12 hours during ten days.

Dosage adjustments

Patients with mild to moderately severe liver function impairment are advised to take the medication cautiously with the tests of the hepatic indicators. Patients with kidney dysfunction with creatinine clearance between 15 milliliters per minute and 30 milliliters per minute should take a half of the standard dosage. People with severe kidney impairment and creatinine clearance less than 15 milliliters per minute should not use the drug.

How does Trimethoprim act?

Trimethoprim destroys the bacterial DNA and the dead bacteria are excreted from the body with urine and feces. If you need more precise and detailed information about the drug’s effect, please read the instruction or the information on the official medication’s website.

Whom Trimethoprim use is contraindicated?

Do not buy Trimethoprim if you have previously used the drug and experienced allergic reactions, have severe kidney impairment or megaloblastic anemia, folic acid deficiency. The drug is contraindicated to be used in children under 1 year of age for urinary tract infections.

It should be cautiously used in people with asthma, liver pathology or disorders associated with thyroid gland.

If you are not sure whether you have any of these conditions, consult your doctor first and tell him or her about all of the symptoms that you have.

Use of the medication during pregnancy and breastfeeding

Trimethoprim is strictly contraindicated for the treatment of urinary tract infections in women during pregnancy and the lactation period.

What are adverse effects of the drug?

As any other drug, Generic Trimethoprim is able to provoke the occurrence of certain side effects. During the clinical trials, it was discovered that the medication can cause headache, allergic reactions (rash, itching, swelling, urticaria), nausea, lack of appetite, pain in the abdomen, diarrhea. In more severe cases, the therapy with the medication can be complicated by aseptic meningitis, malignant exudative erythema, vomiting, anorexia, and nephropathy. Regardless of the severity of the symptoms, you need to inform your doctor immediately as in their occurrence other medication is selected and if severe damage to the health was done, appropriate treatment is prescribed.

Interactions of Trimethoprim with other drugs

Trimethoprim is recommended to be used together with sulfamethoxazole to enhance the effect of both drugs and increase bactericidal properties.

Medications that render toxic effect on the bone marrow enhance the negative effect of the antibacterial drug on the bone marrow as well.

Cyclosporine when taken with Trimethoprim increases the likelihood of nephrotic toxicity complications.

Dapsone use along with Generic Bactrim causes slowed down excretion of both drugs from the body and their increased concentration.

Drugs for the treatment of neoplasms, medications for the prevention and treatment of malaria, anticonvulsants and other drugs that inhibit the synthesis of folic acid, when combined with Trimethoprim increase the possibility of complications such as megaloblastic anemia.

The drug slows down the excretion of Procainamide.

When combined along with Rifampicin, the drug increases its metabolic rate and time of the effect two times.

Slowing down the metabolic rate of anticoagulants of the warfarin group, the drug enhances their effect.

Before you order Trimethoprim, make sure to inform your doctor about all other drugs, supplements, and diagnoses that you have. You may think that you are not using any medications that can negatively interact with the drug but be mistaken.

Overdose of Bactrim (Trimethoprim)

An overdose with the drug is accompanied with nausea, vomiting, diarrhea, dizziness, blurry vision, and central nervous system function impairment. In an extreme overdose, anuria (inability to urinate) and blood in the urine can be observed. Chronic overdose can impair the process of folic acid production and cause the inhibition of the hematopoietic system (leukopenia, thrombocytopenia). In case you notice any of these side effects, call your local poison help line or seek urgent medical assistance.

Where it is better to buy Bactrim?

In some countries, for example, in the U.S. and the UK, all antibiotics are sold with a prescription only. In other countries, such drugs are sold over-the-counter. Moreover, in those countries where the drugs are easy to buy, they are also less expensive. Therefore, if you want to get the drug cheap and without Rx, or even if you have a prescription but still wish to save on the therapy, you can order Bactrim from our online drugstore.

Bactrim shipping by our online drugstore

Rxshop ships all medications internationally. We even offer you free shipping on orders over $199 or its equivalent in other currency. We offer both standard and express whipping with tracking numbers. Find out more about our pricing policy, time of delivery, and special offers from the corresponding section. If you have any questions about the delivery or the pills themselves, do not hesitate to consult our pharmacists via online chat, toll-free phone or email.