Modafinil Case Study

Bipolar Disorder.

One mother of middle age was diagnosed with bipolar disorder. She suffered from stimulant abuse in the past. She was already in remission for the last 5 years. She began to complain about excessive daytime sleepiness. In most cases she wakes up at 7 in the morning, but often gets asleep during a day. Besides, he has some problems with fatigue and loss of motivation. She got the treatment with zolpidem, venlafaxine and lithium. She responded with normal adherence to these drugs.

The basic work in the laboratory and the levels of serum lithium are of acceptable norms. There were not noticed improvements when the dose of venlafaxine was titrated from 225 to 300 mg a day. It was decided to give her a stimulant as a kind of augmenting agent. A she had stimulant abuse in past, she was given Generic Modafinil of 200 mg a day. After some days it was reported about the improvements of her daytime sleepiness and even fatigue. She still had some headache, but it was mild and could be tolerated.

Currently Modafinil is investigated for its potential abilities to manage attention, excessive sleep, weakness and fatigue, cognitive dysfunction which is associated with mood disorders, including bipolar depression and major depression. It is also researched for finding out about its influence on ADHD, cocaine dependence and schizophrenia.

What is its Mechanism?

Everybody pretty knows that Modafinil is the drug which promoted wakefulness and can improve the functioning of cognitive processes. Its off-label indications are becoming more and more popular among the general population. Many buy Modafinil as a must-be drug at home. The most interesting that anyone still can’t understand its mechanism of action. It is considered to enhance wakefulness in a more selective way in comparison with other traditional stimulants such as methylphenidate and amphetamine.

Modafinil doesn’t bind to serotonin, norepinephrine and dopamine. It directly affects hypothalamic areas in the brain which are responsible for the feeling of wakefulness. A lot of preclinical studies show that the medication is able to enhance the activation of neurons in the hypothalamus regions. A number of clinical investigations have revealed that the drug can significantly bring benefits for the working memory, sustained attention and recognition in the healthy grown-up people.

It is suggested to order Modafinil for those who want to improve their quality of life. The medication can improve the overall health condition. According to the Clinical Global Impression of Change, this medication can considerably improve sleep latency and the scores of CGI-C. Currently there is being a lot of investigation conducted in order to find out more about the additional properties of the drug. Many say that it is the drug of the future which will be able to cure a lot of diseases and disorders.