Properties and mechanism of action of Modalert

Benefits of Modalert.

Modalert is a medication, which has a specific effect on the higher integrative functions of the brain: it improves memory, facilitates the learning process, and stimulates intellectual activity. During its research and sales there was observed no side effects, except in rare cases, mild nausea and headache. At this time, the drug is considered safer and more effective than caffeine or amphetamines. It does not cause drug addiction or euphoria (buzz) from the reception, so that psychological dependence is absent or too unlikely.

Unlike stimulants of a mobilizing type, the drug does not cause agitation, exhaustion of functional capabilities of the organism, habituation and addiction. The mechanism of the action of the given medication differs from the one of ephedrine or amphetamine and other similar stimulants. Modalert is not formed in the human body or from the derivatives of amphetamine or ephedrine. It affects different parts of the brain. Perhaps the most important effect is increasing the rate of mental reactions.

The given effect refers to the lower divisions of the intermediate brain, the hypothalamus, where the activation of neural pathways takes place. There the action of orexin or hypocretin is implemented, which plays a meaningful role in regulating the sleep-wake process as messenger substances. In addition, Generic Modalert activates the sympathetic alpha-1-receptors of the human central nervous system, enhances the activity of glutamine and histamine stimulation of transmitters, and increases the effects of serotonin in the brain cortex.

The drug reduces the inhibitory activity of nerve cells, which acts as a transmitter of gamma-aminobutyric acid. It does not lead to excitation of dopamine in the central nervous system, which is believed to be the most powerful effect of amphetamines. The medicine can cause pleasure effect and developing of addiction, but to a less extent than amphetamines. It is well tolerated in therapeutic doses, but side effects can include insomnia, headaches, nervousness, agitation, aggression, increased blood pressure.

Off-label use of Modalert.

It is often taken off label to suppress the need for sleep. The drug is also often used without a doctor's prescription to fight general fatigue not related with the lack of sleep, for instance, by the treatment of attention deficit hyperactivity disorder and as an adjunct to antidepressants (for example, for people with significant residual fatigue). You can easily buy Modalert at any drugstore around the US, Australia or Europe. There are also many reliable online pharmacies where you can order Modalert online, which is quite convenient.