What is Macrobid? How to Treat with Generic Nitrofurantoin.

Generic Macrobid (Nitrofurantoin 100 mg) Medication guide:

More facts about Generic Macrobid (Nitrofurantoin 100 mg):

What is Generic Macrobid? Is there any discrepancy between the original and generic medications?

Macrobid is a trade name under which an antibiotic called Nitrofurantoin is marketed. It is a trade name that is owned by a certain pharmaceutical company and therefore it cannot be used by other drug makers. However, multiple pharmaceutical companies also have capacities to do the same drug. Moreover, the formula of the medication has been around since 1953. However, in order to sell it without infringing copyrights, they come up with different names of their medications. These drugs, for the convenience of customers, are called Generic Macrobid or Generic Nitrofurantoin by the known brand name or the name of the active substance. If you ask any pharmacist for the pills using these unregistered names, he or she will know exactly what you need because they are internationally used names for the drugs identical to the branded drugs which are sold under different names. In order to be sure that the medication you buy corresponds by the composition and effect to the original medication, you can check the active substance, it should be Nitrofurantoin. Usually, the active ingredient names are written below the trade mark on the box of pills.
The antibiotics with this active substance are primarily used to treat urinary tract infections and prophylaxis of infections development after an operation or invasive examination of the urinary tract.

Does Generic Macrobid render equal effect to the original medication?

In general, the purpose of generics has been to make expensive branded drugs affordable to anyone. Moreover, a single pharmaceutical company physically cannot cover the whole world’s need for a certain medication. Therefore, when a company starts manufacturing a generic version of the branded drug, they basically make the same drug - the formula, composition, and the main ingredient are absolutely the same. Based on that, obviously, the effect of the drug you get when you buy Generic Macrobid is absolutely the same as if you bought the drug with the known name on the box of pills.

In what conditions the medication should be used?

You can buy Nitrofurantoin if you are diagnosed with the urinary tract infection, bladder or kidney infection which is caused by a pathogen susceptible to the antibiotic. In order to find that out, susceptibility tests are made. These tests simply require you to give your vein blood for analysis and in a couple of days you will receive the result. Of course, it is better to start using the drug if your doctor prescribes you the antibiotic. If you have a doctor who knows your illness history, he or she will be competent enough to assess the situation and know exactly what antibiotics you used previously which is crucial not to use again the antibiotics you may have developed resistance to.

If for some reason you cannot go to a doctor but you have a chronic condition and are certain that you suffer from an exacerbation, you can also buy Macrobid without a prescription from our online pharmacy.

Treatment courses durations and daily doses

The instruction provides general recommendations. If you have any conditions, please consult your doctor before you start using this antibiotic. Pleas also remember that the use of antibiotics in non-bacterial infections can harm your health significantly.

The average dosage of Nitrofurantoin for adults is 200-400 mg split into 4 intakes a day. The dosage for children is 5-7 micrograms per kilogram of body weight split into four intakes. The average treatment course duration is 7 days. If necessary, the treatment can be continued for 3 more days after the urine tests. In the long-term supporting treatment, the dosages should be reduced.

Dosage adjustments for people with liver or kidney problems

The patients with mild renal insufficiency do not require dosage adjustments. In moderate to severe conditions, i.e. creatinine clearance is less than 60 milliliters per minute, the drug is contraindicated.

If you suffer from liver insufficiency or any other liver condition, you need to consult your health care provider before you buy Generic Nitrofurantoin as the reduced dosages may be prescribed.

Is Nitrofurantoin safe for pregnant and breastfeeding women?

The drug is unsafe during pregnancy and breastfeeding. Therefore, it must not be used.

Contraindications for therapy with Nitrofurantoin

Generic Nitrofurantoin is contraindicated for people with allergy to the drug’s components, anuria (inability to urinate), oliguria (low volume of excreted urine), moderate or severe renal insufficiency, chronic kidney disease, liver cirrhosis, chronic hepatitis, deficiency of glucose-6-phosphate dehydrogenase, and acute porphyria. The antibiotic also must not be taken by pregnant or breastfeeding women and administered to children younger than 1 month of age.

If you are not sure if you have any of these conditions, you should consult your therapist who knows the history of your diseases and can advise on the medication use competently.

What is the drug’s mechanism of action?

Nitrofurantoin is an antimicrobial drug that is a derivative of nitrofuran. It renders bacteriostatic and bactericidal effects, i.e. both stops the reproduction of the bacteria and kills the bacteria. The effects are due to the impact of the drug on the bacterial DNA and RNA proteins’ synthesis. The drug is active against most strains of Escherichia coli, Klebsiella, Enterobacter, and Proteus.

The medication is well absorbed from the gastrointestinal tract. When taken with food, the bioavailability, i.e. the amount of the medication that is active within the body, increases. Nitrofurantoin is excreted in urine; 30-50% is washed out of the body in an unchanged form.

Adverse effects that you can face during the treatment with Nitrofurantoin

As any other drug, Macrobid or its generics can cause various side effects. Hence, when you order Macrobid, you should be prepared that sometimes the drug can be unsuitable for you. The medication frequently causes influenza-like symptoms such as cough, chest pain, dyspnea, interstitial pneumonitis or fibrosis, dyspnea, decreased respiratory function, discomfort in the epigastric region, anorexia, nausea, and vomiting. Other, less frequent adverse effects are diarrhea, headaches, dizziness, sleepiness, changes in the blood indicators, and allergic reactions manifested in rash, swelling, itching, and others.

You should discontinue using the pills and get a consultation of your therapist or urologist if you experience any negative symptoms that you associate with the antibiotic use.

Interactions with other medications

Before you order Generic Macrobid, you need to check with your health care provider that you are not using any medications incompatible with the antibiotic.

For example, concurring use of the drug with nalidixic acid, chalcium channel blockers, and antacids reduces the antibacterial effect of the antibiotic. The drug is also incompatible with fluoroquinolones (group of antibiotics).

Overdose

Overdose of any medication is dangerous so you should try to take the medication at the same time every day to avoid missing the dose or overdosing. The symptoms that you may experience if you overdose with Nitrofurantoin are nausea and vomiting. To cope with the symptoms if they are mild to moderate, you need to drink a lot of water to wash out the excessive medication with urine. If the symptoms are severe, you need medical assistance. Dialysis is an effective procedure in the overdose with the drug.

Where to buy Macrobid?

Obviously, you can buy the medication at your local drugstores but if you don’t have a prescription or simply want to get the medication cheaper, you can order Nitrofurantoin from RXShopMD.com.

Nitrofurantoin shipping terms

We offer standard and express shipping to all corners of the world. The pricing and terms of delivery will meet any budgets and requirements. Find out more in the respective section or consulting our managers via online chat, toll free phone or email.

What is Generic Macrobid? Is there any discrepancy between the original and generic medications?

Macrobid is a trade name under which an antibiotic called Nitrofurantoin is marketed. It is a trade name that is owned by a certain pharmaceutical company and therefore it cannot be used by other drug makers. However, multiple pharmaceutical companies also have capacities to do the same drug. Moreover, the formula of the medication has been around since 1953. However, in order to sell it without infringing copyrights, they come up with different names of their medications. These drugs, for the convenience of customers, are called Generic Macrobid or Generic Nitrofurantoin by the known brand name or the name of the active substance. If you ask any pharmacist for the pills using these unregistered names, he or she will know exactly what you need because they are internationally used names for the drugs identical to the branded drugs which are sold under different names. In order to be sure that the medication you buy corresponds by the composition and effect to the original medication, you can check the active substance, it should be Nitrofurantoin. Usually, the active ingredient names are written below the trade mark on the box of pills.

The antibiotics with this active substance are primarily used to treat urinary tract infections and prophylaxis of infections development after an operation or invasive examination of the urinary tract.

Does Generic Macrobid render equal effect to the original medication?

In general, the purpose of generics has been to make expensive branded drugs affordable to anyone. Moreover, a single pharmaceutical company physically cannot cover the whole world’s need for a certain medication. Therefore, when a company starts manufacturing a generic version of the branded drug, they basically make the same drug - the formula, composition, and the main ingredient are absolutely the same. Based on that, obviously, the effect of the drug you get when you buy Generic Macrobid is absolutely the same as if you bought the drug with the known name on the box of pills.

In what conditions the medication should be used?

You can buy Nitrofurantoin if you are diagnosed with the urinary tract infection, bladder or kidney infection which is caused by a pathogen susceptible to the antibiotic. In order to find that out, susceptibility tests are made. These tests simply require you to give your vein blood for analysis and in a couple of days you will receive the result. Of course, it is better to start using the drug if your doctor prescribes you the antibiotic. If you have a doctor who knows your illness history, he or she will be competent enough to assess the situation and know exactly what antibiotics you used previously which is crucial not to use again the antibiotics you may have developed resistance to.

If for some reason you cannot go to a doctor but you have a chronic condition and are certain that you suffer from an exacerbation, you can also buy Macrobid without a prescription from our online pharmacy.

Treatment courses durations and daily doses

The instruction provides general recommendations. If you have any conditions, please consult your doctor before you start using this antibiotic. Pleas also remember that the use of antibiotics in non-bacterial infections can harm your health significantly.

The average dosage of Nitrofurantoin for adults is 200-400 mg split into 4 intakes a day. The dosage for children is 5-7 micrograms per kilogram of body weight split into four intakes. The average treatment course duration is 7 days. If necessary, the treatment can be continued for 3 more days after the urine tests. In the long-term supporting treatment, the dosages should be reduced.

Dosage adjustments for people with liver or kidney problems

The patients with mild renal insufficiency do not require dosage adjustments. In moderate to severe conditions, i.e. creatinine clearance is less than 60 milliliters per minute, the drug is contraindicated.

If you suffer from liver insufficiency or any other liver condition, you need to consult your health care provider before you buy Generic Nitrofurantoin as the reduced dosages may be prescribed.

Is Nitrofurantoin safe for pregnant and breastfeeding women?

The drug is unsafe during pregnancy and breastfeeding. Therefore, it must not be used.

Contraindications for therapy with Nitrofurantoin

Nitrofurantoin is contraindicated for people with allergy to the drug’s components, anuria (inability to urinate), oliguria (low volume of excreted urine), moderate or severe renal insufficiency, chronic kidney disease, liver cirrhosis, chronic hepatitis, deficiency of glucose-6-phosphate dehydrogenase, and acute porphyria. The antibiotic also must not be taken by pregnant or breastfeeding women and administered to children younger than 1 month of age.

If you are not sure if you have any of these conditions, you should consult your therapist who knows the history of your diseases and can advise on the medication use competently.

What is the drug’s mechanism of action?

Nitrofurantoin is an antimicrobial drug that is a derivative of nitrofuran. It renders bacteriostatic and bactericidal effects, i.e. both stops the reproduction of the bacteria and kills the bacteria. The effects are due to the impact of the drug on the bacterial DNA and RNA proteins’ synthesis. The drug is active against most strains of Escherichia coli, Klebsiella, Enterobacter, and Proteus.

The medication is well absorbed from the gastrointestinal tract. When taken with food, the bioavailability, i.e. the amount of the medication that is active within the body, increases. Nitrofurantoin is excreted in urine; 30-50% is washed out of the body in an unchanged form.

Adverse effects that you can face during the treatment with Nitrofurantoin

As any other drug, Macrobid or its generics can cause various side effects. Hence, when you order Macrobid, you should be prepared that sometimes the drug can be unsuitable for you. The medication frequently causes influenza-like symptoms such as cough, chest pain, dyspnea, interstitial pneumonitis or fibrosis, dyspnea, decreased respiratory function, discomfort in the epigastric region, anorexia, nausea, and vomiting. Other, less frequent adverse effects are diarrhea, headaches, dizziness, sleepiness, changes in the blood indicators, and allergic reactions manifested in rash, swelling, itching, and others.

You should discontinue using the pills and get a consultation of your therapist or urologist if you experience any negative symptoms that you associate with the antibiotic use.

Interactions with other medications

Before you order Generic Macrobid, you need to check with your health care provider that you are not using any medications incompatible with the antibiotic.

For example, concurring use of the drug with nalidixic acid, chalcium channel blockers, and antacids reduces the antibacterial effect of the antibiotic. The drug is also incompatible with fluoroquinolones (group of antibiotics).

Overdose

Overdose of any medication is dangerous so you should try to take the medication at the same time every day to avoid missing the dose or overdosing. The symptoms that you may experience if you overdose with Nitrofurantoin are nausea and vomiting. To cope with the symptoms if they are mild to moderate, you need to drink a lot of water to wash out the excessive medication with urine. If the symptoms are severe, you need medical assistance. Dialysis is an effective procedure in the overdose with the drug.

Where to buy Macrobid?

Obviously, you can buy the medication at your local drugstores but if you don’t have a prescription or simply want to get the medication cheaper, you can order Nitrofurantoin from RXShopMD.

Nitrofurantoin shipping terms

We offer standard and express shipping to all corners of the world. The pricing and terms of delivery will meet any budgets and requirements. Find out more in the respective section or consulting our managers via online chat, toll free phone or email.