Frequently Asked Questions About Combivir (Lamivudine/Zidovudine)

Combivir is a combination medication containing lamivudine and zidovudine, belonging to the class of nucleoside reverse transcriptase inhibitors (NRTIs). It is used in the treatment of HIV infection.

Combivir works by inhibiting the reverse transcriptase enzyme, crucial for the replication of the HIV virus. This helps control the spread of the virus in the body.

Combivir is not a cure for HIV but is an important component of antiretroviral therapy (ART) to manage the virus and maintain immune health.

Combivir is available in tablet form for oral administration, typically taken twice daily.

Combivir is usually part of a combination therapy and is not recommended as a sole treatment for HIV.

While Combivir may reduce the risk of HIV transmission, it is not a substitute for other preventive measures, such as safe sex practices.

If you miss a dose, take it as soon as you remember. However, if it's almost time for the next dose, skip the missed one.

Common side effects may include nausea, headache, and fatigue. These usually subside, but inform your doctor if they persist.

Allergic reactions to Combivir are rare but seek medical attention if you experience symptoms like rash, swelling, or difficulty breathing.

Combivir is often used during pregnancy to prevent mother-to-child HIV transmission, but the regimen should be carefully managed by a healthcare provider.

Combivir may pass into breast milk, so consult with your doctor to assess the benefits and risks before breastfeeding.

Combivir may affect blood cell counts. Regular monitoring is essential to detect any abnormalities.

Combivir can be prescribed to children, with dosage adjusted based on weight and age.

Inform your doctor about all medications, including over-the-counter drugs and supplements, to prevent potential interactions with Combivir.

While rare, Combivir may affect liver function. Regular liver function tests are recommended during treatment.

Lipodystrophy, changes in body fat distribution, is a potential side effect. Notify your doctor if you observe any unusual changes.

Pancreatitis is a rare but serious side effect. Inform your doctor of persistent abdominal pain.

Abrupt discontinuation of Combivir is generally not recommended. Consult with your doctor for guidance on tapering off the medication.

Lactic acidosis, a rare but serious condition, may occur. Seek medical attention for symptoms like weakness, rapid breathing, or nausea.

Peripheral neuropathy is a potential side effect. Report any tingling or numbness to your healthcare provider.

Combivir may be part of post-exposure prophylaxis. Consult with a healthcare provider promptly after potential exposure.

Insomnia is a rare side effect. Taking the medication earlier in the day may help minimize this effect.

Changes in weight, either gain or loss, may occur. Monitor your weight and inform your doctor of significant changes.

Combivir may be considered for occupational exposure prophylaxis. Seek immediate medical advice after exposure.

While uncommon, Combivir may affect kidney function. Regular monitoring is advised.

Mood changes, including depression, have been reported. Inform your doctor if you experience persistent mood alterations.

Diarrhea is a potential side effect. Stay hydrated and inform your doctor if it becomes severe.

Combivir may be considered for non-occupational exposure prophylaxis. Consult with a healthcare provider promptly after exposure.

Cardiovascular issues are rare but inform your doctor of any history of heart problems.

Combivir is not typically used for pre-exposure prophylaxis. Discuss suitable PrEP options with your healthcare provider.