What is Arava? How to Treat with Generic Leflunomide.

Generic Arava (Leflunomide 10 mg) Medication guide:

More facts about Generic Arava (Leflunomide 10 mg):

What is the medication sold under the brand name Arava?

The brand name Arava was registered for a substance called Leflunomide by the developer of the formula. The medication is an anti-rheumatoid basis drug that renders anti-proliferative (anti-spreading), immunosuppressive, and anti-inflammatory effects. It is included in the World Health Organization’s List of Essential medicines as it is considered one of the most important medications in a contemporary healthcare.

The developer patented the drug and received an approval for the use of the medication in several forms of arthritis in the U.S. in 1998. However, the exclusive right of the developer to make and market the medication had already ended so other manufacturers got the right to use the formulation to produce their own drugs. These medications are the same but are sold under different names and at lower prices.

The medication can be combined with other preparations used to suppress the inflammation in the joints such as nonsteroidal anti-inflammatory drugs, acetylsalicylic acid, and corticosteroids.

The medication is not advised to be used in women of fertile age as it can cause birth defects in case pregnancy occurs during the medication use. Therefore, if you are in this group of patients, you need to take care of good contraception when you plan to buy Arava and start the therapy.

What is the medication sold as Generic Arava?

As we have mentioned before, the formula of the mediation is known by all producers of medications because it is no longer protected by the know-how. However, the manufacturers of medicines who hadn’t developed the formula themselves need to use different names than the developer. There are numerous trade names for Leflunomide (the active agent of brand drug Arava). For instance, the same medicine can be sold under the names Lefumide, Leflunomidum, Lefunomide, lefno, and others. But you don’t need to memorize them as you can simply look for the brand name plus the word “generic” in front of it. For instance, if you look at Google for a way to buy Generic Arava, you will find multiple search results. These results are online pharmacies that sell the cheaper, generic versions of the most popular medications. If you opt for a reliable online pharmacy like ours, you will enjoy the best effect at a low and attractive price that is several times lower than at the regular drugstores.

When should Generic Arava be bought and used?

The active ingredient of the medications that can be found looking for this name is effective for the therapy of effective rheumatoid arthritis and psoriatic arthritis. It is used for the elimination of the disease symptoms and the general condition of an affected individual. It also prevents or slows down the formation of edge erosion of joints and narrowing of joint slots.

The usual treatment of arthritis made with acetylsalicylic acid, nonsteroidal anti-inflammatory medicines and low doses of corticosteroids can be continued during the therapy with Generic Arava (Leflunomide).

If you are diagnosed with one of the conditions the pills are used for, you can buy Leflunomide without a prescription from our med store and start the therapy but it would be wiser to discuss the possibility and benefit of such therapy with your health care provider first if he or she didn’t appoint you this particular medication. The pills can be contraindicated for you or incompatible with other medicines that you take so you need to check it with your physician too.

For whom Generic Arava is contraindicated?

The medication is contraindicated if you are allergic to the drug’s components, in severe liver dysfunction, immunodeficiency including HIV, severe disorders of bone marrow hematopoiesis or anemia, leukopenia, thrombocytopenia (except for the condition caused by rheumatoid arthritis), severe bacterial infections, moderate to severe renal failure, severe hypoproteinemia (including nephrotic syndrome).

Besides, the medication is strictly contraindicated for pregnant and breastfeeding women and children and adolescents younger than 18 years of age. Women of fertile age also are not recommended to use the medication because in case pregnancy occurs during the therapy, the drug can cause severe birth defects. If you are in this group, you must take care of reliable contraception for the period of therapy when you buy Generic Leflunomide or discuss the medication replacement with another less potentially dangerous one.

What adverse effects can be caused by the medication use?

All medicines without an exception have a possibility to provoke adverse reactions occurrence. Sometimes it is caused by the intolerance of the drug, sometimes by the combination with incompatible medications or substances, overdose, incorrect time of intake, and so on. The most likely side effects that can develop when you order Arava and start using the pills are elevation of the arterial pressure, loose stools, nausea, vomiting, loss of appetite, dry mouth, stomatitis, ulceration of the lips, hair loss, eczema, dry skin, skin rash, swelling, and others.

In case you develop an allergic reaction, you should immediately discontinue the intake of pills. In other symptoms, notify your physician and follow his or her advice.

How to use Generic Arava pills?

The treatment with the drug is started with a loading dosage of 100 mg taken once a day for three consecutive days. This is made due to the long half-life of the active substance and this increased dosing for a short period of time allows to quickly achieve the equilibrium state of the plasma concentration of the active agent. Then the dosage is reduced to 20 mg a day in both rheumatoid and psoriatic arthritis. In case the dosage is poorly tolerated, i.e. severe adverse reactions occur; the daily dosage can be lowered to 10 mg taken once a day.

The therapeutic effect starts to manifest within 4-6 weeks since the therapy start and can amplify within the next 4-6 months of the therapy. The medication must be taken for long periods of time so it is reasonable to order Generic Arava in advance from our online pharmacy to save on the drug and the visits to your doctor. Your healthcare provider will tell you when you should stop using the pills based on your tests.

With what medications or substances must not you combine Arava pills use?

Before you purchase the pills and start the therapy, you should verify either with your healthcare provider or by yourself using the drug encyclopedia that you don’t use any medicines that are contraindicated to be combined with Leflunomide. There are no strict contraindications but the pills are not recommended to be combined with some other medicines because the likelihood of adverse effects increases. For instance, the possibility of side effects increases in combined use or if you lately used hepatotoxic (toxic for the liver) or hematotoxic (toxic for blood system) drugs or started using them after the therapy with Generic Arava when the drug hadn’t fully excreted from the body.

The use of activated carbon and cholestyramine accelerates the quick excretion of the medication and the lowering of its effect.

Leflunomide and methotrexate used at the same time can cause the increase in the liver enzymes production.

Potential increase in prothrombin time is possible in the combined use of the medication with warfarin.

The concurrent use of Generic Arava with antimalarial drugs used to treat rheumatic diseases, gold preparations, penicillamine, azathioprine and other immunosuppressive drugs is not fully studied and therefore is not advised.

If you are unsure whether you use any of the medications that can influence the efficacy of this anti-arthritis medication, make sure to consult your doctor before you order Leflunomide.

What will happen if you overdose with Arava?

In case of the use of an increased dosage of the medication, you can start suffering from pain in the abdomen, nausea, vomiting, liver dysfunction, anemia, and leucocythemia.

The excessive dosages of the preparation are effectively washed out with the activated carbon and cholestyramine. If you took these drugs but still suffer from severe side effects, seek emergency help.

Where to buy Arava?

Since the medication must be taken for a long time, it would be much cheaper to order Generic Leflunomide instead of the branded medicine. Opting for a generic you will enjoy the same effect but at a significantly lower price. The best generics can be found at our online pharmacy.

Shipping of Arava

Rxshop pharmacy ships preparations everywhere in the world in 14-35 days. The express shipping is from one to two weeks and the standard is a bit longer but cheaper.