What is Cardizem? How to Treat with Generic Diltiazem.

Generic Cardizem (Diltiazem 30 mg) Medication guide:

More facts about Generic Cardizem (Diltiazem 30 mg):

When Cardizem or Generic Diltiazem can be used?

Your doctor can prescribe you or recommend this drug if you have any kind of ischemic heart disease, including angina pectoris, after a myocardial infarction, diabetic nephropathy, fibrillation and flutter of the ventricles, arresting paroxysms of atrial fibrillation, paroxysmal supraventricular tachycardia, and others.

If your doctor says that you can use it for hypertension, you can also buy Cardizem (Diltiazem) and use it either as prescribed by your doctor, or if she or he doesn’t give you strict indications, as said in the instruction.

The medication is also used after a kidney transplant and during immunosuppressive therapy.

What is the mechanism of action of Generic Diltiazem?

The medication is an antagonist of calcium ions. It blocks calcium channels of type L and inhibits the entering of calcium ions into the phase of depolarization of cardiomyocytes and vascular smooth muscle cells (reduces intracellular calcium volume). Reduces contractility of the myocardium, the myocardium demand of oxygen through several mechanisms - decrease in energy consumption by myocardial cells, reduction in the activity of the system of formation and conduction of excitation with parallel suppression of tachycardial reactions, reduction in the tone of peripheral arteries and arterioles with a parallel decrease of the systemic vascular resistance, slow down of atrioventricular conduction and the decrease of excitability of the atrioventricular node; tension relief from the blood vessels.

The use of Generic Cardizem causes negative chronotropic action, i.e. slows down the heart rate, slows down atrioventricular conduction and reduces the excitability of the atrioventricular node.

The antianginal effect is related to the diminishing of the end-diastolic pressure by expanding the peripheral veins and reducing the blood inflow to the right atrium and subsequent sparing of the myocardium of preloads, dilation (extension) of the coronary blood vessels and improved oxygen supply to the heart.

The effect of the drug is similar to Verapamil but Cardizem’s effect on the smooth muscles of the vessels is a bit more pronounced. Compared to Nifedipine, the peripheral vasodilator action (dilatation of the lumen of blood vessels) and reflex tachycardia (rapid heart rate) effects are less pronounced.

How to use the drug?

Before you buy Generic Diltiazem, make sure to clarify with your doctor that this drug is suitable for your condition, accompanying conditions, age, and medications that you already use. Ask him or her, what dosages are preferable namely for your case.

Here we are providing general instructions that are taken from the medication label. The following dosage regimens are suitable for adults only. Take into account that there are different dosages per pill and forms of medications – capsules, coated capsules, and tablets. The dosages may vary based on the form of medication (pills or capsules). The pills or capsules should be taken at the same time every day during the therapy course.

- Hypertension: the starting dosage is from 120 to 240 mg taken once a day. The dosage can be gradually increased if necessary. The optimal maintenance dosage is from 120 to 540 mg taken once a day. The maximum daily dosage is 540 mg. The maintenance dosage for extended release coated capsules is from 240 to 360 mg once a day. The maximum daily dosage for extended release coated capsules is 480 mg a day.

- Angina pectoris prophylaxis: the standard starting dosage is from 120 to 180 mg taken once a day. The dosage can be gradually increased if the effect is insufficient every week or two of continuous therapy. The maximum daily dosage is 540 mg a day. For extended release coated capsules the maximum dosage is 480 mg. For extended release tablets the maximum daily dosage is 360 mg a day.

Immediate release pills are used as follows: 30 mg 4 times a day before meals. The dosage can be gradually increased till the minimum effective one. The adjustment can be made every 1-2 days of the therapy. The optimal maintenance dosages are from 180 to 360 mg a day taken in 3-4 intakes.

- Congestive heart failure: the standard starting dosage is from 120 to 180 mg taken once a day. The dosage can be increased if the effect is insufficient every week or 2 weeks of the therapy. The maximum daily dosage is 540 mg. The maximum daily dosage for extended release coated capsules is 480 mg a day, for extended release pills – 360 mg a day.

Immediate release pills are used as follows: 30 mg 4 times a day before meals. The dosage can be gradually increased till the minimum effective one. The adjustment can be made every 1-2 days of the therapy. The optimal maintenance dosages are from 180 to 360 mg a day taken in 3-4 intakes.

In mild to moderate kidney and liver conditions the dosage adjustment isn’t required.

The medication is used in intravenous infusions for the following conditions: atrial fibrillation, atrial flutter, andsupraventricular tachycardia. The administration of the medication must be made by certified healthcare specialists. The dosages are chosen individually based on the patient’s weight.

Whom the drug is contraindicated?

You should not buy Cardizem and inform your doctor if: you have pronounced bradycardia, the sinus node weakness syndrome, cardiogenic shock, atrioventricular blockade of the II-III degree, Wolff–Parkinson–White syndrome, arterial hypotension, chronic heart failure of stage III-III, acute heart failure, severe liver and/or kidney dysfunction, hypersensitivity to the drug.

The drug is contraindicated for children and pregnant and breastfeeding women.

What side effects can Cardizem (Diltiazem) cause?

When you start therapy with any drug, you must be attentive to any symptoms that accompany it. Some of the adverse reactions may be simply unpleasant, while others are indicating that the drug is unsuitable for you and can even lead to serious health problems. To avoid them, stop using Generic Cardizem (Diltiazem) and call our doctor if you have any of these or other side effects: transient hypotension, bradycardia, palpitations, fainting, eosinophilia, headache, dizziness, weakness, fatigue, , constipation or diarrhea, nausea, heartburn, hyperplasia of the gingival mucosa, peripheral edema, erectile dysfunction, sweating, redness of the skin, skin rash and itching, and others.

With what medications the drug should not be combined?

If you use any drugs when you buy Cardizem, make sure to inform your doctor that you are taking any medications.

Potentially dangerous combinations of the medications include Diltiazem-based drugs with beta-blockers, quinidine and other antiarrhythmic drugs of class I-a, cardiac glycosides, inhalation anesthesia, lithium, indomethacin, and furosemide.

The medication increases the concentration of carbamazepine, theophylline, quinidine, valproic acid and digoxin, ciclosporin in the blood plasma.

What should you do in the overdose with Cardizem (Diltiazem)?

If you overdosed, seek medical assistance immediately as severe heart-related adverse reactions can occur. The symptomatic treatment is indicated in the hospital under a doctor’s supervision.

Where to buy Cardizem (Diltiazem) online?

The drug is sold with Rx in the U.S. and some other countries though it is an over-the-counter drug in others. To buy the medication without prescription and save on the visits to your doctor and the difference in price, you can order it from our online drugstore. We sell brand-name medication and its cheaper generic analogs. If you are not sure what drug is more suitable for you, you can get a free consultation of our pharmacist.

Cardizem (Diltiazem) shipping by RXShopMD

Rxstore ships to every corner of the world. We have multiple loyal customers from the U.S. and the UK who receive their prescription drugs by mail without any trouble. We offer two shipping options, standard and express. Find out more about it and our special discounts in the FAQ section or consult our customer support managers via online chat.