What is Zestril? How to Treat with Generic Lisinopril.

Generic Zestril (Lisinopril 2.5 mg) Medication guide:

More facts about Generic Zestril (Lisinopril 2.5 mg):

What is Generic Zestril? Is there a difference between it and the brand drug?

The term is used for all medications with the same active ingredient and formula but manufactured by different pharmaceutical companies who register their own names for the drugs they make.

The medication mostly known in the U.S. as Zestril is marketed all over the world but under different trade names. The drugs are identical so you don’t have to worry about the differences in their effects and safety. To check if the drug you want to buy is the same as the brand-name drug, check its active substance which should be Lisinopril, and the dosage per pill of the active substance.

When should the drug be used?

You can buy Zestril if your doctor prescribes you the brand-name medication for the treatment of hypertension, heart failure, nephropathy, myocardial infarction, and as a prophylaxis after a heart attack. However, your doctor can decide that the effect of the medication will be also beneficial in other conditions, so do not be surprised that you are advised to use this medication if you don’t have any of the listed conditions.

How to use the drug? Is there a difference in use of the brand drug and generic?

First of all, if you buy Generic Lisinopril pills with the dosage per pill that your physician or cardiologist recommended, you should follow the prescription as the drug is identical to the medication sold under the brand name Zestril. Secondly, though in this medication guide you can find generally recommended dosages, it is still advised to consult your doctor so he or she will be able to select the dosage individually.

Use in adults:
- The therapy of hypertension is started with 10 mg taken once a day. Subsequently, the dosage can be increased to 40 mg once a day if the desirable effect is not achieved and the drug doesn’t cause adverse reactions. However, it is preferable to find the minimum effective dosage and stick to it. The maximum allowed dosage is 80 mg a day;
NOTE: if you already use diuretics, the starting dosage is 5 mg a day. If the effect of the medication is insufficient, sometimes it is preferable not to increase the dosage but maintain the lower dosage and add diuretics (water pills) to the therapy;
- The therapy of congestive heart failure is started with 2.5 mg a day. If the drug is well tolerated, the dosage can be gradually increased to 5 mg a day, and further. The maximum daily dosage is 40 mg a day;
- The therapy of myocardial infarction is typically started not less than 24 hours after infarction happened. The starting dosage is 5 mg. Two days after infarction, the dosage should be 10 mg a day which is maintained throughout the entire treatment course for not less than 6 weeks;
NOTE: in patients who suffer from hypotension, i.e. lowered blood pressure, the starting dosage for the condition is 2.5 mg a day. If after the intake hypotension persists, the medication should be withdrawn;
- The therapy of nephropathy is started with 10 mg per day. The dosage can be increased to 20-40 mg a day every 3-5 days if the drug is well-tolerated.

Treatment of children:
- The drug can be used in children aged 6 or more years for hypertension treatment.  You can buy Zestril or a generic version of the medication of a standard formulation but create suspension crushing the pills and mixing them with water to get the right dosage.

The starting dosage is 0.07 milligrams per kilogram of the body weight a day but not more than 5 mg a day. The dosage can be subsequently increased if the medication is well-tolerated and the desirable effect is not achieved to 0.61 milligram per kilogram of the body weight but more than 40 mg a day. The drug is contraindicated for children with creatinine clearance less than 30 ml per minute.

Dosage adjustments for different groups of patients

Elderly patients should start the therapy of hypertension with a reduced dosage of 2.5 mg a day. The dosage can be elevated to 5 mg a day if the drug is well tolerated and the desired effect is not achieved but not sooner than one or two weeks after the therapy start. The maximum daily dosage should not exceed 40 mg a day.

People with mild to moderate kidney failure do not need dosage adjustments. People with severe kidney failure and creatinine clearance less than 30 ml per minute but more or equal to 10 ml per minute should start the therapy with the dosages two times lower than the recommended ones. The maximum daily dosage is 40 mg a day if according to the kidney tests the drug doesn’t influence the renal function. People with creatinine clearance less than 10 ml per minute should use 2.5 mg a day.

People with liver dysfunction can take the medication without dosage adjustments yet if jaundice or increased level of hepatic enzymes is observed should stop using the drug.

What is its principle of action of the medication?

Before you buy Lisinopril you may want to find out more about how the action of the medication is achieved. In this article we explain it in a simplistic way so if you need more detailed information please refer to the complete instruction.

Lisinopril, the active substance of the medication is an angiotensin-converting enzyme inhibitor. It constrains the effect of the natural enzyme, a catalyst found in the body, on another substance (angiotensin) transformation. When angiotensin transforms freely to its form called type 2, it causes blood vessels narrowing and causes blood pressure elevation, and as a result, heart problems. Preventing this transformation, the drug helps to maintain normal blood pressure within all blood vessels in the body and especially in the heart.

The use of medication during pregnancy and breastfeeding

The tests of the medication in animals confirm that the drug cannot be used during pregnancy as it can result in fetus fatality or development of life-threatening defects. It is also highly not recommended to use the medication if you breastfeed.

Whom the drug is contraindicated?

Do not order Generic Zestril for yourself if you are pregnant, breastfeeding, are prone to swelling, or have diabetes. The drug should not be used in children younger than 6 years and people with lowered blood pressure.

What side effects can Zestril (Lisinopril) cause?

As any other medication, Zestril or a generic drug with the same composition can cause possible side effects. They include headache, dizziness, general weakness, hypotension, cough, labored breathing, skin rash, diarrhea, and others.

In order to know how to react in case any of these or other adverse reactions occur, make sure to consult a healthcare specialist before starting the therapy.

What drugs should you avoid using along with Zestril (Lisinopril)?

Before you order Generic Lisinopril, check this list of medications with which the risk of side effects increases. If you are unsure whether any of the drugs you use have the substances listed here, consult your doctor.
- The medication slows down the excretion of lithium and can cause its toxicity increase;
- Nonsteroidal anti-inflammatory drugs, estrogens, and adrenomimetics lower the antihypertensive effect of the drug;
- Potassium-sparing diuretics or any drugs that have potassium in them can cause hyperkalemia when combined with Zestril;
- Other medications that lower blood pressure enhance the antihypertensive effect of the drug;
- Antacids and colestyramine reduce the absorption of Lisinopril in the digestive tract;
- Gold preparations (gold salts) combined with the medication can cause nausea, vomiting, hypotension, and other negative symptoms;
- Insulin and oral hypoglycemic drugs increase the risk of hypoglycemia.

What should you do in the overdose with Zestril (Lisinopril)?

The main symptom of an overdose is blood pressure lowered below norm. The treatment of an overdose requires symptomatic treatment made in a hospital.

Where to buy Zestril (Lisinopril)?

You can get the medication much cheaper than at your local drugstores and even without a valid prescription if you order Zestril from our online drugstore. We sell brand-name drugs and generics without prescriptions because our office is located in the country where they are over-the-counter drugs.

Zestril (Lisinopril) shipping by Rxshop

We will ship your order to any corner of the world. All products are accompanied with tracking numbers. Find out more about our special offers including free shipping from the FAQ section of our website.