Varditra: Premium Vardenafil for Erectile Dysfunction Treatment

Generic Varditra (Vardenafil 10 mg) Medication guide:

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Your Racing Heart and Erection Problem May Not Be a Panic Attack. Something later found out will turn out to be very helpful, but there is no need to wait until you see someone, who will come up with that brilliant thought, while you are definitely suffering. With left eye problem came dizziness and I started having more palpitations in the head, too. This would usually happen to me with anything happening to the head. This time, I was driving a car and suddenly I felt something was rising up in the middle of the chest and then a strong thump gripped my whole body and ached. Once the same scenario was playing just when I was standing somewhere, so it was not the fatigue leading to a collapse. And to think that panic attack is coming from nowhere. So I turned to a psychiatrist.

What is Varditra?

Erectile dysfunction is the most common sexual problem in men. It describes a problem where a man cannot get or maintain hard enough for sexual activity. It is caused by not having enough blood flow to the penis, which prevents the penis from becoming hard. With sexual stimulation, you can have an erection at any time from 25 minutes up to four to five hours after taking it. Varditra can help you get an erection when you are sexually excited. You will not get an erection just by taking the pill. Varditra does not cure erectile dysfunction. It is a treatment for erectile dysfunction. Varditra does not protect a man or his partner from sexually transmitted diseases, including HIV. Varditra is not for women or children. Varditra does not help you get an erection if you are not having problems with having an erection or if you have an erection at all.

Varditra is a medicine used to treat erectile dysfunction (ED) in men. This leaflet gives you the answers to the most common questions about Varditra. This Medication Guide does not take the place of talking with your doctor. You and your doctor should talk about Varditra when you start taking it and at regular checkups. If you do not understand the information or have questions, talk with your doctor or pharmacist.

How does Varditra work?

The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. Grapefruit can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details. Tell your doctor if your condition does not improve.

Read the Patient Information Leaflet provided by your pharmacist before you start taking vardenafil and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth as directed by your doctor, usually as needed. Take vardenafil, with or without food, about 1 hour before sexual activity. Do not take more than once daily. Doses should be taken at least 24 hours apart.

Vardenafil is used to treat male sexual function problems (impotence or erectile dysfunction-ED). In combination with sexual stimulation, vardenafil works by increasing blood flow to the penis to help a man get and keep an erection. This drug does not protect against sexually transmitted diseases (such as HIV, hepatitis B, gonorrhea, syphilis). Practice "safe sex" such as using latex condoms. Consult your doctor or pharmacist for more details.

Usage and Dosage

If you are pregnant, nursing a baby, or are under 18 years of age, consult your doctor before taking VARDITRA™. If you are a woman who is pregnant, avoid taking VARDITRA™, as its safety for in utero development has not yet been established. VARDITRA™ is not intended for use in adult women. VARDITRA™ is not indicated for use in pediatric populations. Keep in mind, VARDITRA™ is only intended for use as directed by your doctor. Follow your doctor's orders exactly, and read the medication’s directions that are included with your prescription. Do not take more or fewer doses of VARDITRA™ than your doctor has prescribed. Contact your doctor or pharmacist with any questions. If you take VARDITRA™ with a high-fat meal, its effects may be delayed or lessened. By following a healthy diet, you will stay active while taking VARDITRA™ to treat your ED.

The maximum recommended dosing frequency is once per day. You should take VARDITRA™ about one hour before an intended sexual activity. Swallow the tablet with one full glass of water. Avoid drinking grapefruit juice or eating grapefruit, as this may increase the chance of experiencing side effects of VARDITRA™. Please inform your doctor if you have any sexual concerns after the treatment has begun or even before it is started. Do not change or discontinue any treatment without first consulting your doctor. Do not take VARDITRA™ if you are currently being treated with ritonavir or indinavir. Also, do not take vardenafil if you have been advised by your doctor to avoid sexual activity under any medical condition. Sexual activity might put extra strain on the heart, especially if it is already weak from heart disease, high blood pressure, stroke, or other chronic illnesses. If you experience a sudden loss of vision in one or both eyes, stop using VARDITRA™ and seek emergency medical help immediately.

Recommended dosage of Generic Vardenafil

No evidence of possible drug-item modification occurred in the ejaculate. It does, however, it is unlikely that any small amount will pass to the small number of sex. Since Varditra only affects phosphodiesterase-5 function, this drug caused no effect on spermatogenesis and sperm motility. In four cases, patients of different degrees, additional helps were asked to clarify the relationship between zindan Nigeria agreement sudden hearing loss and impotence treatment. No cause-effect relationship between both events. There is no evidence of probable, hence the drug class phosphodiesterase-5 initiators, therefore, the cause of hearing loss. In reporting any adverse events, this is important, to help monitor circumstances and patients with adverse events should either stop taking Varditra/report or seek medical help when using another cause emergency medical pharmacological agent.

For most patients, the recommended starting dose of vardenafil (Varditra) is 10 mg taken orally, approximately 60 minutes before sexual activity. The dose may be increased to a maximum recommended dose of 20 mg based on efficacy and side effects. The maximum recommended dosing frequency is once per day. The recommended dose, and the proposed dosing frequency given above, is not recommended for patients with moderate hepatic insufficiency (Child-Pugh B). For patients with mild hepatic insufficiency, the recommended dose is 5 mg. Concomitance of a potent CYP3A4 inhibitor such as ketoconazole or ritonavir significantly increases plasma concentrations of vardenafil. Therefore, the concomitant use of adequate doses of ketoconazole or ritonavir and Levitra vardenafil tablets is unsuitable. The highest daily dose of vardenafil is 20 mg. In eight primary placebo-controlled clinical studies of 12 weeks duration, an average 15% of the patients received Varditra 10 mg and took an average of 83% of the doses.

How to take Varditra

If you use more Varditra than it was recommended, contact a pharmacy or a doctor for immediate advice. If you accidentally take a pill that is not in the proper blister package, store this information in a different place where children cannot reach it. Varditra should be stored in a childproof pharmacy to prevent children from using Varditra. If a child uses Varditra, the child could die from a heart attack, and in case of allergies, there is a high risk of children having a sudden illness with symptoms like diarrhea, nausea, and difficulty breathing. It is not known if Varditra can harm unborn children if their mother takes the pill.

Be aware of the following recommendations when taking Varditra: Take the whole pill with a glass of water. The effects of Varditra are most felt 30-60 minutes after taking it. Ingest Varditra 25-60 minutes before actually wanting to have sex. Once you have taken Varditra, you can have sexual intercourse during a four to five-hour period. The effects of sexually stimulated by Varditra will end 8-12 hours after taking the pill. This doesn't mean that you will have an erection for 8-12 hours, only that you can get an erection for up to 8-12 hours. Do not take Varditra together with juice that contains grapefruit or alcohol. Avoid taking with heavy and greasy meals. Wait at least one hour after your last meal before taking the pill.

Important instructions for Vardenafil usage

Patients are advised to contact their healthcare provider for the correct amount of treatment. Vardenafil can be taken with or without meals. Use vardenafil orally disintegrating tablets exactly as prescribed by healthcare providers. Men with moderate liver and kidney problems are advised to begin treatment with vardenafil 5 mg. Adjustment of the dose of the drug is recommended when an increase in waist circumference is noticed. In patients with mild hepatic function, the starting dose should be reduced to vardenafil 5 mg (depending on individual tolerance). Vardenafil is contraindicated for patients with severe liver function. It has been shown that the use of cimetidine and erythromycin increases vardenafil levels. A starting dose of 5 mg vardenafil should be applied in patients who are taking moderate inhibitor protease of CYP 3A4, and then 10 mg in patients who are stable in the treatment of ketoconazole, itraconazole, and erythromycin.

This medicine is intended only for men (18 years or older). Vardenafil does not cure erectile dysfunction (ED). It is not possible to determine whether these events are directly related to Vardenafil or to other factors. If you experience sudden decrease or loss of vision, stop vardenafil dosing immediately and contact your healthcare provider. Patients should be stable on alpha-blocker therapy prior to initiating a PDE5 inhibitor. Vardenafil can be taken with or without meals. Use vardenafil orally disintegrating tablets exactly as prescribed by healthcare providers.

Side Effects and Precautions

Men taking Vardifra live too long to give any significance to possible side effects. In addition, you should always consult with your doctor and inform your doctor of any side effects that you may be experiencing. Your doctor is the best person to decide if further consultation is necessary. Furthermore, having a sincere, open and clear discussion with your doctor is vital when dealing with a medical condition such as erectile dysfunction. Your physician can provide explanations and treatment to suit individual needs. Always keep all medication out of the reach of children. Never take medication that was not prescribed for you.

A sudden decrease or loss of vision has been reported in men taking Vardifra in situations similar to those experienced with Cialis and Levitra. If you experience such symptoms, you should stop taking Vardifra and consult with a physician immediately. Other side effects associated with Vardifra are low blood pressure and priapism, a condition with a long duration. The most common side effects of Vardifra are headache, stuffy nose, dizziness, and indigestion. If you experience other serious side effects, you should stop taking Vardifra and seek immediate emergency attention.

It is important to consult with your physician before taking Vardifra because your physician is the best person to decide if Vardifra is right for you, and is the best person to determine if there are other medical conditions that may prevent you from using the medication.

Common side effects of Varditra(Vardenafil)

To determine whether vardenafil side-effect profiles differ from sildenafil profiles, a meta-analysis was carried out using data from both randomized controlled studies and observational studies. The study included 3 efficacy and safety studies with a total of 2,606 men between 16 and 95 years of age. Men with any significant chronic physical illness, surgical history, or known physical abnormality were excluded. Vardenafil and sildenafil have been shown to have similar risks for headaches, flushing, and visual disturbances. Data from included studies implied that risks of vardenafil-induced headaches decrease as patients get older. Finally, data analysis suggested a statistical difference between the risk of headache, as outcomes of the overall comparison between vardenafil and sildenafil were significant.

The list of common side effects of vardenafil is generally comparable to that of sildenafil and tadalafil. Common adverse reactions recorded in the package insert for vardenafil include headache, flushing, rhinitis, and visual disturbances, all of which are also common with the use of sildenafil. In addition, it is worth mentioning that differences between reports of side effects of vardenafil, specifically vardenafil-odt, and sildenafil suggest potential differences between agents. This is consistent with findings reported in studies that have assessed satisfaction with their ED treatment.

Serious side effects and when to seek medical help

Generic Vardenafil should not be used by patients with a heart condition and those who are always recommend that you talk to a healthcare provider before you start taking vardenafil, if you recently have had a stroke, heart attack, irregularities heart rhythms or experienced symptoms of heart failure such as shortness of breath and swelling of the lower legs, that is necessary for you to consult with your doctor, before taking a new medicine, if you have been advised to avoid sex due to heart problems. For cardiovascular risks, such as heart attack, bleeding or stroke can increase the use of vardenafil. Therefore if you have a condition such as these, before any sexual activity; using vardenafil, you should consult with your doctor.

• Male patient with a heart condition and is distressed because chest pains occur and he has had an erection that can't be bent down or have lasted for too long (more than 4 hours).
• Patient faints and feels dizzy; or experiences a sudden change in hearing or vision or in the way things look like having problems identifying which of the following; or have difficulty breathing or swallowing.
• You are having difficulty breathing.

For a small number of people, taking vardenafil disintegrating tablets can result in severe side effects. For others, the side effects may not occur but it is always advisable to call your healthcare provider. The following symptoms are uncommon but could indicate the presence of a serious condition, so if you experience any of them, stop taking this medication and seek medical help immediately.

Precautions and warnings for Varditra usage

If you need to avoid sexual intercourse for health reasons, your doctor may recommend sexual or physical activity. Do not take vardenafil if you are also using a nitrate medicine for chest pain or heart problems, including nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, or some recreational drugs such as amyl nitrate (potentially causing significant hypotension if taken with a regular dose of vardenafil). Vardenafil is taken when required, around 25 to 60 minutes prior to launching sexual activity. Vardenafil can be taken with or without meals. Vardenafil can help reach a community or maintain an erection if the male user is sexually excited. Vardenafil will not cause an erection unless the penis user is sexually excited. Vardenafil should not be taken for longer than four hours.

Ask when you remove the old packaging. Store vardenafil at room temperature and away from moisture and heat. Do you think that causes symptoms? If you have a sudden decrease or loss of vision or hearing, check with your doctor immediately with tadalafil, tell your medicine on time? Do not use Vardenafil with similar medications, such as sildenafil or tadalafil. Follow the instructions of your doctor.

If you need to avoid sexual intercourse due to health problems, your doctor may recommend sexual intercourse or physical activity. Do not take vardenafil if you are also using a nitrate drug for chest pain or heart problems, including nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, or some recreational drugs such as amyl nitrite or nitrate. Blood pressure can cause sudden and serious blood pressure drop. The symptoms of this medication are not expected to be harmful to an unborn baby.

Patients should tell their healthcare providers that they take Vardenafil or similar medicines before receiving a new prescription. Vardenafil can cause dizziness and vision changes in rare cases. When you take a Vardenafil tablet to treat male impotence, vardenafil can cause your blood pressure to lower suddenly to an unsafe level. If your family tells you that you have a condition called retinitis canada or a certain eye problem, Vardenafil may cause changes in the way objects look or cause sudden loss of vision in one or both eyes.

Interactions and Contraindications

Tamsulosin did not cause orthostatic hypotension when administered in combination with low or standard doses of vardenafil. Vardenafil also did not cause IMPs in healthy volunteers, to chloroquine and hydroxychloroquine, which are known substrates of the cytochrome 3A4 enzyme. This suggests that the observed increase in vardenafil concentration can be expected if vardenafil is used in combination with a potential CYP3A4 inhibitor. Interactions were studied with ethyl alcohol (0.5 g/kg). Plasma concentrations were not significantly affected. Administration of a single 20 mg dose of vardenafil did not affect the extent — t d the weak interaction of amino acid valtrex tablet in a double-blind placebo-controlled study of 17 healthy volunteers (14 men, 3 women) aged 18-53 years, the pharmacokinetics of vardenafil were not significantly affected by taking a single dose of valtrex flavored diphenhydramine and diphenhydramine, doses for oral suspension (25 mg 50 mg per 100 ml, respectively) two hours before taking the drug.

A study was conducted in which the interaction of vardenafil (20 mg) with alfuzosin (10 mg) was considered. There were no clinically significant differences in the average maximum blood pressure (maximum decrease in blood pressure). Also, the frequency and severity of side effects do not increase. QTc alteration was not studied, so caution is recommended when administering the drug to patients at risk for prolongation (e.g. patients with congenital or acquired QTc prolongation, taking antiarrhythmics of classes Ia and III or taking non-antiarrhythmic drugs that promote QTc prolongation). When taking vardenafil in a dose of 5 mg and 10 mg in the steady state when used in combination with the therapeutic doses of terazosin (5-10 mg daily), alfuzosin (10 mg daily) or tamsulosin (0.4 mg daily) there were no significant changes in diastolic BP and SBP compared with placebo.

Medications that interact with Varditra

Generic Vardenafil may amplify the blood pressure lowering effects of antihypertensive agents. When vardenafil was taken as recommended (on an empty stomach), meals did not affect 67% of patients. Vardenafil use made 5% of patients stop a meal due to poor symptoms. Consuming alcohol did not appear to impact vardenafil absorption, except for the likelihood of lowered blood pressure to be stricken. Symptoms of a heart attack include chest, shoulder, neck, or jaw pain; numbness of an arm or leg; severe dizziness, headache, nausea, stomach pain, or vomiting; fainting; or vision changes. Prior to consuming vardenafil, notify your doctor if you get either chest pain or palpitations. A doctor can better determine how dangerous your heart issue could be. Your doctor might not be able to prescribe you a different medication for erectile dysfunction if they know you are vulnerable to developing either of the two conditions.

Vardenafil can cause your blood pressure to drop suddenly to an unsafe level if it is taken with certain other medicines. You could get dizzy or faint. If you are taking a type of medication called alpha blockers, your doctor may start you on a smaller dose of vardenafil. Do not use vardenafil if you are using any form of organic nitrate or nitric oxide donors such as amyl nitrite. This is a group of medicines (nitrates) used in the treatment of angina pectoris (chest pain). Vardenafil has been shown to amplify the hypotensive effects of nitrates.4

Conditions and medications contraindicated with Generic Varditra

Special warnings and special precautions for use 5 mg film-coated tablets. White circular biconvex film-coated tablets (diameter 10 mm) embossed with the alphanumeric Varditra on one side and 5 on the other side of the tablets. 10 mg film-coated tablets. Yellow circular biconvex film-coated tablets (diameter 10 mm) with a slightly aromatic flavor embossed with the alphanumeric Varditra on one side and 10 on the other side of the tablets. 20 mg film-coated tablets. Orange-yellow circular biconvex film-coated tablets (diameter 10 mm) with a slightly aromatic flavor embossed with the alphanumeric Varditra on one side and 20 on the other side of the tablets.

Concomitant use of alpha-blockers: Alpha-blockers, other than tamsulosin 0.4 mg daily, should not be taken concomitantly with Varditra. Alpha-blockers: The concomitant use of Varditra with alpha-blockers can lower blood pressure significantly, leading to symptomatic hypotension. Patients older than 65 years of age: Concomitant use of Varditra with alpha-blockers, and moderate hepatic impairment: Use Varditra starting dose of 5 mg. Varditra dose should be reduced to 5 mg in patients with moderate hepatic impairment (Child-Pugh B) and used at a maximum of once in a 24-hour period. Severe renal impairment (creatinine clearance <30 mL/min) and hemodialysis: Use Varditra starting dose of 5 mg. Varditra dose should be reduced to 5 mg in patients with severe renal impairment or patients undergoing hemodialysis.

Nitrates: Vardenafil may potentiate the hypotensive effects of organic nitrates in the treatment of stable angina pectoris. Therefore, Varditra is contraindicated in patients who are using a GC stimulator, such as riociguat. There is a potential for cardiac risk of sexual activity in patients with preexisting cardiovascular disease. Therefore, treatments for erectile dysfunction, including Varditra, should not be used in men for whom sexual activity is inadvisable due to their underlying cardiovascular status (hardiness).

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Sources: Garza K, Goble C, Brooke J, Jay C. Framing the community data system interface. Proceedings of the 2015 British HCI Conference 2015.