Natural Sleep Enhancement with Melatonin (Restfine)

Generic Melatonin (Restfine 10 mg) Medication guide:

More facts about Generic Melatonin (Restfine 10 mg):

Cognitive functions can be low for people working night shifts. Melatonin has been proven to help increase mental function skills, which will be helpful for people working night shifts, and the sleep they will get will be of better quality. Along with treating sleeping disorders, melatonin has been used to help treat various patients with cancer. A major problem associated with end-stage cancers are tumors located within the brain. Many of these patients experience a decrease in quality of sleep; melatonin could help alleviate these symptoms without the harsh side effects of sedatives or other drugs. Melatonin has been used to treat various sleep disorders, and it has been quite successful so far! It has also been successful in combating the drowsiness caused by blood pressure medications. Because melatonin can increase the effectiveness of blood pressure medications, it may be possible to decrease the dosage of these medications when taking melatonin, which could result in the patient saving money. Restfine is a hormone that is naturally produced in the body and it is used mainly to regulate sleep and wakefulness. It is believed that the levels of melatonin in the body naturally increase in the evening, and it is this which triggers an increase in tiredness and a decrease in alertness. It also helps to regulate the body's temperature during sleep, and it has been proven to help combat insomnia and other sleep disorders.

What is Melatonin?

Generic Melatonin is a hormone found in the body of humans, as well as in animals and plants. In humans, it is produced by the pineal gland, an endocrine gland located in the center of the brain. At night or in the dark, the pineal gland releases melatonin, which is then readily taken up by the blood. The secretion of melatonin drops to a low level during the day, especially in the afternoon. Generic Restfine regulates the sleep-wake cycle and helps the body to determine when it's time to go to sleep. This internal clock is greatly affected by the amount of light the body is exposed to. During the shorter days of the winter months, the body may produce melatonin either earlier or later in the day than usual. This change can lead to symptoms of seasonal affective disorder (SAD), including depression, fatigue, and a change in energy level. Melatonin is also a powerful antioxidant. It has been widely accepted that melatonin in the cells is the most efficient way to neutralize free radicals. It has been found to be more effective than vitamin C, vitamin E, or glutathione. In the case of a typical antioxidant, the normal action is to sacrifice itself (the antioxidant) to neutralize a free radical; then the spent antioxidant must be recycled or regenerated in the body. Melatonin, however, has been found to not only be 2 times more efficient than vitamin E, but it regenerates various spent antioxidants, including vitamin C. It is very versatile in that it is a soluble and nonsoluble antioxidant. Because of its versatility and its oncostatic action, melatonin has been found to be a potential broad spectrum treatment for many disease states where free radicals and antioxidants are an issue.

How does Melatonin work?

There are two different types of melatonin products, modified release and immediate release. The body has a natural preference for a stable, continuous release of hormones. Restfine release melatonin has been developed to mimic the profile of the body's own melatonin release. Immediate release melatonin is useful for people who have difficulty falling asleep. It is particularly effective in resetting the body's sleep-wake cycle, such as shift workers or those suffering from jet lag. Melatonin is a hormone that helps regulate the sleep/wake cycle, an internal pacemaker that controls the timing and our drive for sleep. It is produced by the pineal gland in the brain and released at night to make falling asleep easier. Normally, melatonin levels begin to rise in the mid- to late evening, remain high for most of the night, and then drop in the early morning hours.

Who should take Melatonin?

Melatonin is recommended for individuals who experience sleep issues. As mentioned previously, melatonin is involved in the regulation of the sleep-wake cycle. Although sleep patterns change throughout our lifetime, there are a variety of conditions which may cause a disruption to our natural sleep cycle. This includes the blind who may lack light cues to set their internal body clock, therefore having difficulty in determining the difference between day and night. Shift workers who change their sleep schedule causing a disruption in their sleep cycle and people suffering from jet lag which is a temporary condition experienced by travelers who have crossed several time zones which can leave them disoriented, sleepy, irritable, and unable to concentrate. Other conditions which could affect your sleep cycle in which melatonin may be helpful include sleep problems in children and adolescents, the elderly, those with a mild cognitive impairment and dementia. Finally, melatonin has been effective in improving sleep in individuals who suffer from a mild to moderate case of a circadian rhythm sleep disorder, a persistent or recurrent pattern of sleep disruption which is primarily caused by an alteration of the internal circadian time-keeping system and leading to sleep disturbance and excessive sleepiness.

Usage and Dosage

Restfine is a herbal medicine which contains melatonin (N-acetyl-5-methoxytryptamine), which is a hormone. The recommended dosage is 1 to 2 tablets daily, half to one hour before going to bed. Increase the dosage to 2 tablets only if, after 4 weeks, this is found to be necessary and still wake up feeling unrefreshed. Tablets should be swallowed whole. Also, during travel, take 1 tablet half to one hour before the expected sleep period on the first day of travel and on the following few days after arrival at the destination. Can be taken for up to 13 weeks. Recommended dosage of melatonin varies according to the different condition or different individuals. In older adults, for insomnia (two-stage release): 2 mg of a specific product (Target, 2-Stage Release Melatonin) taken at bedtime for sleeping problem. This improvement is better compared to taking 2 mg regular melatonin. Young adults feel improvement after consuming melatonin in small doses starting from 0.3 mg until 1 mg may optimize their sleep and not exceed 3 mg. Children with retarded sleep phase syndrome are given melatonin 3 mg/5 ml and for visually impaired children are taking 3 mg per day. Adolescents with attention deficit hyperactivity disorder (ADHD) are given 5 mg melatonin tablet for a week, decreased to 3 mg per day second week and the maintenance dosage is 3 mg per day. Patients with insomnia or sleeping disorder by discontinuing benzodiazepines take 5 mg per day for 6 months from stopping the previous medication. High or multiple sclerosis patients are given with 10 mg or less daily dose. Cancer patients who suffer with chemotherapy side effects are given an adequate dose comparatively with their problem, generally considered a low dose. A patient with brain injury or posttraumatic stress disorder (PTSD) using 3 mg tablet. Duration taken whether short or long term depends on the condition. In short, to minimize sleeping time problems before sleeping and long term taken according to the resolution of sleeping problems.

How to take Melatonin

You should take melatonin only when you are ready to go to bed. If you take it too early before you are ready to go to sleep, it may worsen your drowsiness. This is especially important if you are taking melatonin to help with sleep problems related to a work schedule change or jet lag. If you are uncertain about what time to take melatonin, go to bed earlier rather than later the first time you try it. If you have epilepsy, you should avoid melatonin. Always tell your doctor about any over-the-counter medications you may be taking. This is especially important if you are taking any medications to thin the blood or if you are taking sedatives. Every person may respond differently to a medication or treatment. Your response to the recommended dose of this particular medication is an improvement in your ability to fall asleep at night. If you feel that the melatonin is causing drowsiness during the day or having any other negative effects, you should reduce the dose. If you feel that the melatonin is not helping you fall asleep and is not causing any drowsiness, you may want to increase the dose. The possibility that melatonin may improve your sleep and energy during the following day is something you should consider when experimenting with the dose. High melatonin doses may decrease body temperature and hormone levels. Follow your body's response and adjust the dose accordingly.

Precautions and warnings

When taking melatonin, avoid driving or operating dangerous machinery within five hours of taking the supplement. Melatonin can cause drowsiness. Also, avoid a high intake of alcohol while taking melatonin because it can increase the effects of the supplement. There is also evidence to suggest that melatonin should not be taken by those with epilepsy. Some research has suggested that melatonin may reduce the length of time it takes to fall asleep. This may not be a positive side effect for some individuals. The body naturally has a daily cycle of temperature regulation. Melatonin can alter core body temperature in some individuals by acting on the hypothalamus. These effects can be significant in the evening and can cause a disturbance in sleep for some individuals. Core body temperature has also shown to be reduced in women by the effect of melatonin and can provide enough of a change to influence a pregnancy. Due to these effects, it is advised that melatonin is not used by pregnant or nursing women. Melatonin may also influence hormone levels and the immune system, and it is not known if there are any long-term effects of melatonin usage. Long-term effects have not been established, and therefore it is not advised that melatonin is used by individuals who are not chronically affected by sleep schedule disturbances.

Possible side effects of Melatonin

A double-blind, placebo-controlled study proved that melatonin has an effect on mood. The study found that the occurrence of severe depression was low during melatonin administration. Another study provided evidence that melatonin decreased daytime anxiety. Melatonin can affect hormone levels. Some animal research has suggested that melatonin can lower FSH levels and slow down poor ovarian response and deterioration of reproductive tissues. How melatonin affects you can vary. If disoriented or unusual effects occur, cease using and consult your doctor. Melatonin might trigger morning drowsiness. For some individuals, melatonin can cause feelings of drowsiness that linger long after the waking hour. If taken close to bedtime, it can bring on sleepiness and drowsiness too much, grogginess, reduce alertness, and reduce reaction time. Heat palpitation increased heart rate might occur if too much melatonin is taken. Lower the dose to see if the palpitations stop. More rare side effects include itch or development of skin rashes, mood swings, and diarrhea. If any of these occur, consult your physician immediately. Note that it is not known if it is the melatonin that is causing the condition or if it is a result of something else.

Benefits and Effectiveness

In the older population, it has been shown that minimal dosages of melatonin are the most effective in improving quality of sleep. In a lined study, melatonin was shown to be much more effective than the hypnotic drug triazolam. The trial led to the conclusion that melatonin significantly improved sleep quality at a very low dose (0.1 mg) and is desirable for an aging population due to the low risk of dependency. This information was further confirmed by an alternative randomized study, which provided data showing that melatonin was more effective than a placebo, increasing total sleep time and quality. Demonstration of safety is also highly beneficial for older people, and increased amounts of data have shown that short and long-term use of melatonin is safe and effective for people of all ages. Melatonin has been proven to be an effective aid in helping people to get to sleep. A meta-analysis was conducted and revealed that melatonin demonstrates a significant sleep-inducing effect in adults, including beneficial effects on sleep latency and all other sleep parameters. This data was shown to be highly significant, and clinicians could be confident that melatonin has an effect greater than placebo in decreasing sleep onset latency and increasing sleep efficiency. Sleep onset latency was reduced on average by 7 minutes with melatonin.

Sleep improvement with Melatonin

This part of the Melatonin Medication Guide outlines what Restfine is, how it works, and its effectiveness. Treatment for sleep disorders should only be initiated after a careful evaluation of the disorder and appropriate non-pharmacological measures. Safety and effectiveness of Restfine in children or adolescents has not been established. Starts: Melatonin is a hormone secreted by the pineal gland in the brain from tryptophan, a dietary amino acid, and is converted at night. The major role of melatonin is the regulation of the sleep-wake cycle. During the day, the levels of melatonin are barely detectable. They begin to rise in the evening after sunset and reach their peak during the middle of the night. Then they fall in the early hours of the morning. Light decreases the production of melatonin. In humans, melatonin has been used most commonly to treat phase shifts such as jet lag and changes in work schedule, but it is also used in the treatment of delayed sleep phase syndrome, sleep problems in children with neuro-developmental disorders including visual or mental retardation, and chronic sleep onset insomnia.

Managing jet lag with Melatonin

Normally, melatonin is taken after reaching the final destination, at the desired sleep time in the new time zone, and continued for 2-5 days. The theory is that the proper administration of melatonin will mimic the endogenous secretion rhythm and aid in the adaptation of the new time cycle. Using melatonin in this manner has been shown to be effective in hastening the resynchronization of the body's circadian rhythms and aiding in the alleviation of jet lag symptoms. Melatonin is noted to be effective in preventing or reducing jet lag. Travelers crossing five or more time zones, who consumed melatonin, reported overall improved sleep quality. Also, elderly patients have a slower and lower production of melatonin, often resulting in various sleep disturbances. Melatonin supplementation has been shown to be a very effective treatment for this age group. Unfortunately, the improvement of sleep onset and sleep maintenance may not transfer to an improvement in subjective measures of daytime sleepiness.

Other potential benefits of Melatonin

Research is being conducted to determine whether melatonin can be used effectively to improve sleep in a wide variety of circumstances in which sleep is disturbed. These circumstances include sleep problems in children and adolescents, shift work, and sleep disturbances common in the blind. A number of studies have shown that melatonin is not only useful in correcting delayed sleep phase syndrome, but that it is also effective in other circadian rhythm sleep disorders. Another possible application would be in the treatment of sleep disturbances in individuals who are quitting smoking or ceasing the use of benzodiazepine sedative drugs. There is also evidence to suggest that melatonin may be useful in inducing sleep in people with reduced melatonin receptor function. These various studies are still in the early stages, and further research involving melatonin and sleep is needed.

Where to buy Melatonin Generic Restfine online

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