What is Aygestin? How to Treat with Generic Norethindrone Acetate.

Generic Aygestin (Norethindrone Acetate 5 mg) Medication guide:

What is Generic Aygestin? Is it different from the brand-name medication?

The medication sold under the trade name Aygestin in the U.S. is as well made and marketed by other pharmaceutical companies. All drugs with the same composition and effect but under a different registered trade name are called Generic Aygestin by Cipla or Generic Norethindrone Acetate. The drugs are identical but their prices can differ significantly. Generics are cheaper because they are made using already made formula. Their manufacturers also rarely invest in advertising. Therefore, if you want to save on the treatment and your insurance doesn’t cover the medication such as Norethindrone Acetate, you can buy Generic Aygestin from our online pharmacy much cheaper than your local pharmacies sell the medication and without a prescription. Nevertheless, we highly advise you to consult your doctor before you start the therapy with this medication because it is a hormonal drug that if used improperly or in conditions in which it is contraindicated can cause serious harm to your body.

As for the legal status of the generics, they are legal in all countries and even promoted by the World Health Organization to make the medications affordable for all groups of people. However, in the U.S. only several generics of Aygestin are approved to be marketed. It is so not because other generics are inferior but because their manufacturers decided to choose other markets to sell their drugs in and didn’t even apply for the medicines registration and approval in the U.S. Since all drugs in the country are highly overpriced, we can certainly say that buying a generic from another country is much more beneficial.

What is Norethindrone Acetate?

This is the name of the active substance of Aygestin, Primolut-Nor, Gestakadin, Milligynon, Primolut N, Styptin, and their generics. The substance is a hormonal agent, is a steroidal progestin, used in a variety of gynecological conditions in women.

When should Aygestin be used?

The medication is used in a variety of conditions treated by gynecologists. In this section of the article you can find conditions in which the medicine is prescribed but note that the dosages and intake regimens differ significantly from a condition to condition. Therefore, before you buy Aygestin you need to find out your precise diagnosis, exclude the presence of the contraindications for the drug use and get the instructions from your doctor on the dosages, length of the treatment course, and manner of intake of the medication.

The drugs based on Norethindrone Acetate are used for: premenstrual syndrome, benign fibrocystic breast disease, dysmenorrhea with shortening of the secretory phase, dysfunctional uterine bleeding, painful menstruation caused by incorrect uterus position, inflammation, and so on, primary and secondary amenorrhea, cystic glandular hyperplasia of the endometrium, endometriosis, adenomyosis, uterine fibroid, infertility, miscarriage, prevention and cessation of lactation, postponement of menstruation, climacteric syndrome, and contraception.

What is the mechanism of action of Aygestin (Norethindrone Acetate)?

The medication is a progestin hormone, a synthetic gestagenic hormonal drug that contains the ovary's yellow body hormones or their synthetic analogues. It inhibits proliferative activity in hyperplastic endometrium, i.e. benign unhealthy growth of the tissues of uterus, promotes secretory transformation, development of decidual stromal reaction and atrophic changes in the epithelium of glands and stroma. It oppresses the secretion of gonadotropic hormones by the pituitary gland.

Aygestin is well absorbed when taken orally. It reaches its maximum concentration in the blood plasma in 2 hours after the intake. It is metabolized in the liver and excreted with urine (up to 70%) and feces.

How to use the brand or Aygestin (Norethindrone Acetate)?

It doesn’t matter whether you order Aygestin or its generic; the dosages are the same for both medications. However, in the majority of cases they are selected individually. Here you can find the general recommendations for different conditions but please consult your doctor before you start taking the pills.
- Premenstrual syndrome: 5-10 mg a day or 1-2 tablets starting from the 16th day of the cycle till the 25th day of the menstrual cycle.
- Dysfunctional uterine bleeding and cystic glandular hyperplasia (proliferation) of the endometrium: 5-10 mg a day or 1-2 tablets during 6 or 12 days after the therapy start. To prevent relapses, the drug is used in combination with an estrogenic drug (for example, Ethinylestradiol) in the same dosage from 16th to 25th day of the menstrual cycle.
- Endometriosis: 1 pill a day from 5th to 25th days of the menstrual cycle or a half of the pill every 2-3 weeks during 4-6 months.
- Climacteric syndrome: the daily dosage is 1 pill a day usually along with an estrogenic drug (for example, Ethinylestradiol 25-50 Mcg a day) for a long duration therapy.

Whom the drug is contraindicated?

Do not you order Generic Aygestin if you are currently pregnant, are diagnosed with cancer, have a propensity to thrombosis, suffer from acute thrombophlebitis or thromboembolism, bleeding from the genitalia or urinary tract of unclear origin, metrorrhagia (bleeding from the genitalia between periods) of unknown origin, cholestasis (including history), acute liver condition, liver dysfunction, hepatitis, or cirrhosis.

The drug should not be also used in women allergic to the medication’s components and before puberty. The drug is not recommended during pregnancy unless it is used for a prevention of miscarriage.

Adverse reactions Generic Aygestin can cause

The use of the pills can cause the following side effects: nausea, vomiting, bleeding from the genitalia between periods, swelling, increased tiredness, abnormal sensations in arms or legs such as itching, numbness, tickling, pricking, etc., weight gain, breast enlargement and stiffness, allergic reactions. Long-term therapy can cause the development of thrombosis. Therefore, if your doctor tells you to use the medication continuously, make sure to visit him or her at least once a month.

Incompatible medications

The medication’s effect and time of effect are lowered with the use of barbiturates.

If you currently use any medications including vitamins and supplements, inform your doctor about all of them before you buy Aygestin and start using it. Certain medications can lead to serious complications especially if you use Norethindrone Acetate during pregnancy. For example, Isotretinoin used along with the medication can cause life-threatening defects in the fetus or a baby.

Symptoms and treatment of the overdose

It is extremely dangerous to overdose with this medication especially if you use it during pregnancy as it can lead to the death of the baby. The common symptoms of the overdose include nausea, vomiting, vaginal bleeding, dizziness, and others. Even if you don’t have these symptoms but know that you took an increased dosage of Aygestin, seek medical assistance immediately.

Is the brand drug and generic different in effect?

No, the drugs we sell are identical to the brand medication. However, you should cautiously check the active substance of the drug your doctor prescribed you and its dosage per pill and only then order Generic Aygestin because some manufacturers sell different dosages per pill.

Where to buy Aygestin?

The drug is expensive in the U.S. and is sold with a prescription only. If your doctor prescribes you to use the drug for a long treatment course, you can order the pills from our online pharmacy to save both on the pills themselves and visits to your doctor for a refill prescription.

Generic Aygestin shipping by Rxshop

Our online drugstore specializes in medications selling all over the world. Therefore, we ship internationally. We offer both standard and express shipping with tracking numbers. You can also enjoy free shipping if you order pills on the sum equal or greater than $199.